The Startup Genome, in partnership with Telefónica Digital, engaged more than 50,000 startups across the world to understand where, outside of the proven testing ground of Silicon Valley, entrepreneurship takes hold. Simultaneous with a global explosion of entrepreneurship has been a burst of new startup ecosystems around the world, and a newfound maturity in others. While Silicon Valley is still the world's largest and most influential start-up ecosystem, flourishing communities in other U.S.